Scientists create human sperm from stem cells


LONDON - British scientists claimed Wednesday to have created human sperm from embryonic stem cells for the first time, an accomplishment they say may someday help infertile men father children.


The technique could in 10 years allow researchers to use the basic knowledge of how sperm develop to design treatments to enable infertile men the chance to have biological children, said lead researcher Karim Nayernia, of Newcastle University, whose team earlier produced baby mice from sperm derived in a similar way.


The research, published in the journal Stem Cells and Development, was conducted by scientists at Newcastle and the NorthEast England Stem Cell Institute.


Stem cells can become any cell in the body, and scientists have previously turned them into a variety of new entities, including cells from the brain, pancreas, heart and blood vessels.
Some experts challenged the research, saying they weren’t convinced Nayernia and his colleagues had actually produced sperm cells. Several critics also said the sperm cells they created were clearly abnormal.


“I am unconvinced from the data presented in this paper that the cells produced by Professor Nayernia’s group from embryonic stem cells can be accurately called ’spermatazoa,” said Allan Pacey, a senior lecturer in andrology at the University of Sheffield.
Pacey said in a statement that the sperm created by Nayernia did not have the specific shape, movement and function of real sperm.


Azim Surani, a professor of physiology and reproduction at the University of Cambridge said the sperm produced by the Newcastle team were “a long way from being authentic sperm cells.”
Nayernia said the cells “showed all the characteristics of sperm,” but his group’s intention was simply to “open up new avenues of research” with their early findings, rather than using the sperm to fertilize eggs.


Robin Lovell-Badge, a stem cell expert at the National Institute of Medical Research said that despite the questions raised, Nayernia and colleagues may have made some progress in obtaining human sperm from embryonic cells.


Nayernia said creating embryos from lab-manufactured sperm is banned by British law.
He said they only plan to produce sperm to study the reasons behind infertility, and will not fertilize any eggs.


Some lawmakers said provisions should be made to allow sperm derived from stem cells to be tested as part of potential fertility treatments.

Obesity may be a risk factor in swine flu

ATLANTA - Some swine flu cases in Michigan are raising questions about obesity's role in why some people with infections become seriously ill.


A high proportion of those who have gotten severely ill from swine flu have been obese or extremely obese, but health officials have said that might be due to the fact that heavy people tend to have asthma and other conditions that make them more susceptible. Obesity alone has never been seen as a risk factor for seasonal flu.

Meanwhile, the government is ready to announce another $1 billion in orders for swine flu vaccinations.

Health and Human Services Secretary Kathleen Sebelius said Sunday she will announce Monday that Washington has approved another billion dollars to buy components of the vaccine. Sebelius said that research is under way to provide a safe and effective vaccine to fight a flu strain that could be a pandemic.

Sebelius and other top officials are bracing for fall's flu season. She says leaders are watching the Southern Hemisphere for clues how serious the U.S. flu season might be.
Sebelius appeared on CNN's "State of the Union."

Complications in obese patientsIn a report released Friday, health officials detailed the cases of 10 Michigan patients who were very sick from swine flu in late May and early June and ended up at a specialized hospital in Ann Arbor. Three of them died.

Nine of the 10 were either obese or extremely obese. Only three of the 10 had other health problems. Two of the three that died had no other health conditions.

This hardly settles the question of whether obesity is its own risk factor for swine flu. It's possible the patients had undiagnosed heart problems or other unidentified conditions.
Still the finding was striking, investigators acknowledged.

Also remarkable were that five of the patients developed blood clots in their lungs, and six had kidney failure. Those complications have been seen in some swine flu patients before, but not usually in such a high proportion.

"Clinicians need to be aware that severe complications can occur in patients with the novel H1N1 virus, particularly in extremely obese patients," said Dr. Tim Uyeki, a flu expert at the Centers for Disease Control and Prevention.

Uyeki was a co-author of the report, released by a CDC publication, Morbidity and Mortality Weekly Report.

Also on Friday, the CDC said the number of U.S. swine flu cases has surpassed 37,000 and deaths have risen to 211.

The numbers rose from the 170 deaths and nearly 34,000 confirmed and suspected swine flu cases reported last week.

Those are lab-confirmed and probable infections. CDC officials believe those cases — which sought treatment and underwent testing — are just the tip of the iceberg. They estimate more than 1 million Americans have been infected with the virus so far, though many probably had only a mild illness.

Swine flu is the predominant flu type circulating currently, with nine states reporting widespread cases, down from 10 a week ago.

The pandemic was first identified in California in April. Since then a total of more than 94,000 cases have been reported in more than 100 countries, according to the World Health Organization.

Your best face: Beautiful skin at 40 and beyond


The best skin of your life may well be ahead of you. Sure, with each passing decade, you face fresh challenges in your quest for a radiant complexion: There are the newfound crow's feet in your 40s, the postmenopausal dryness in your 50s, and the sagging that sets in by your 60s. But the right products and procedures will prepare you to meet these challenges head-on.
"These days, it's perfectly reasonable to expect your skin to get better as you age — no matter what the date on your driver's license," says Dr. Ranella Hirsch, president of the American Society of Cosmetic Dermatology and Aesthetic Surgery and a cosmetic dermatologist in Cambridge, Mass.
Still, knowing what's right for you — from the most potent creams to the latest lasers — can be confusing. That's where this decade-by-decade guide comes in. It's filled with everything you need to know, including exactly what to use when. Follow along and your skin's future will look very bright.
Your 40s: treat, tone and texture
Best home treatments Embrace retinoids: These vitamin A derivatives boost collagen production (which softens fine lines and minimizes pores). Retinoids rev up sluggish cell turnover, so skin becomes smoother and more radiant, and dark spots fade. Prescription versions such as Renova yield noticeable changes after about eight weeks; retinol, the strongest over-the-counter option, takes 12 weeks. Choose a product formulated with up to 1 percent retinol, the highest amount available OTC, depending on your skin's tolerance. Try Remergent Advanced Retinol Therapy ($56; remergentskin.com) and Roc Retinol Correxion Deep Wrinkle Serum ($20; drugstores). Ease in by using a retinoid every third night for at least two weeks. Apply it every other night for the next two weeks, ramping up to nightly application. Summer's the ideal time to get started on a retinoid — the increased humidity tempers dryness that might occur as your skin acclimates.
Exfoliate regularly: Once you've built up to a nightly retinoid application, boost its benefits by substituting in an alpha-hydroxy acid twice a week. "Both ingredients exfoliate, leaving skin brighter and smoother," says New Orleans-based dermatologist Dr. Mary Lupo. "But because they stimulate cell renewal in different ways, you'll get maximum improvement using both." If skin is dry, choose an AHA formulated with moisturizing lactic acid.
Consider hydroquinone: This agent, which inhibits the production of melanin, is one of the most effective ways to fade blotchiness, says Hirsch. OTC creams contain 2 percent HQ, which lightens subtle discoloration over several months. Rx versions boast 4 percent, and daily spot treatment can diminish dark patches in six to eight weeks. "Keep in mind, though, that a single afternoon spent unprotected in the sun can undo all that hard work," says Wechsler. Use HQ only for three months. After that, maintain results with a skin lightener that contains kojic acid or licorice extract.
Turn to the pros Reduce brown spots: Intense pulsed light (IPL) employs a broad wavelength of light to target brown spots and red areas, destroying them without damaging the upper layers of the skin; you may look a little pink for an hour after treatment. Four to six monthly sessions at about $400 each should be enough to even out your complexion; a maintenance session every 6 to 12 months keeps up the results.
Restore your glow: A series of LED (light-emitting diode) treatments, either on their own or in conjunction with IPL, uses painless light energy to minimize fine lines, reduce pore size, diminish dark spots, and give skin a smoother texture. There's no downtime: You sit in front of a panel of 2,000 tiny pulsing lights for up to 40 minutes; results become more noticeable after three weeks. "LED thickens the skin, so it looks more luminous when light bounces off it," says Dr. David Goldberg, a clinical professor of dermatology and director of laser research at Mount Sinai School of Medicine. A recent study published in the Journal of Drugs in Dermatology also showed that the device promotes new collagen formation and decreases inflammation that causes collagen to break down. Six monthly treatments at about $100 each and twice-yearly touch-ups are recommended.
Erase lines: Botox is the surest way to smooth creases you're already noticing and prevent more. It temporarily relaxes facial muscles so they can't move and create wrinkles. "Botox retrains your muscles, so the effects last longer and longer," says Goldberg. "Some patients who start when they're 45 are coming in only twice a year by the time they're 50." Each treatment costs approximately $400, and results last about 4 months.
Your 50s: hydrate and plump The average age of menopause is 51, and with the drop in hormones, skin becomes parched and brown spots increase. Deeper folds, including the "smile" lines that run from the corners of the nose to the corners of the mouth, develop as skin loses underlying fat. This loss also "hollows out" the under-eye area, says Dr. Kenneth Beer, an assistant professor of dermatology at the University of Miami.
Best home treatmentsSwitch to a gentler cleanser: Replace oil-stripping gel cleansers or bar soaps with a creamy face wash. Choose double-duty moisturizers. "Look for formulas that contain a humectant to draw water in and an occlusive to create a barrier that prevents it from evaporating," says Dr. Arielle Kauvar, a clinical associate professor of dermatology at New York University Medical Center. Try L'Oréal Paris Age-Perfect Pro-Calcium Restorative Hydrating Cream ($20; drugstores) and the Body Shop Wise Woman Regenerating Night Cream ($34; thebodyshop.com).
Rethink your retinoid: If you haven't already, switch to Renova or Atralin; both are moisturizing.
Take care of your eyes: Collagen and fat loss under delicate eye skin makes crow's feet more apparent. Plump lines with a nightly application of an eye cream. Look for one with silicone, an emollient that temporarily "spackles" fine lines, says Dr. Heidi Waldorf, an associate clinical professor of dermatology at Mount Sinai School of Medicine.
Turn to the pros Plump lines and lips: Filling materials injected into your skin enhance hollow areas. For a natural look, choose a filler that contains hyaluronic acid, formulated from a substance found in skin. Both Restylane and Juvederm last about 6 months and are ideal for plumping the smile lines, lips, and under-eye area. Perlane, which is thicker, is used to fill deeper folds and sunken cheeks and lasts up to eight months.
Prevent wrinkles: Botox softens new folds and increases the longevity of fillers by minimizing the muscle movement that can cause them to dissipate.

Arms central to US-Russia talks


US President Barack Obama and his Russian counterpart Dmitry Medvedev are expected to announce nuclear weapons cuts when they meet later in Moscow.
Officials on both sides were quoted as saying a document had been agreed, though Russia said it was not final.
Both men say they want significant cuts - possibly down to 1,500 warheads each.
In addition Russia has been pressing Mr Obama to scrap a US plan for a missile defence shield in Europe. Afghanistan and Iran are also on the agenda. President Obama will hold talks with Vladimir Putin, currently prime minister and formerly president, on Tuesday. Many analysts say he is still in the driving seat in the Russian government.
Both sides have made clear their desire to improve, or "reset", relations between Washington and Moscow.
But BBC diplomatic correspondent Jonathan Marcus, who is in Moscow, says that is not going to be easy given the different perceptions of their national interests the two sides bring to the table.
Under the previous Bush Administration, relations between Washington and Moscow were almost as bad as during the Cold War, so there is ample opportunity for improvement, he adds.
'Difficult situation'
Mr Obama flew out of Andrews Air Force Base aboard Air Force One on Sunday evening, together with his wife and two daughters. He is due to begin his visit by laying a wreath at the Grave of an Unknown Soldier near the Kremlin wall, before talks with Mr Medvedev.
The Russian president said in an interview for Italian media released on Sunday that US missile shield plans for Europe put a "very prominent nuclear country like Russia... in a difficult situation".
Arms control will top the agenda of the summit. The Soviet-era Start I accord expires in December.
The White House co-ordinator for weapons of mass destruction, Gary Samore, ruled out any final agreement on renewing Start being reached this week, but he did see an "announcement" being made.
"I think you will see an announcement that indicates some progress toward reaching that objective," he told reporters.
On Afghanistan, the US is confident of obtaining Moscow's approval for flying troops and weapons through Russian airspace.
President Obama will also meet Russian journalists and civil society activists.
Low-key feel
A University of Maryland opinion poll released on Sunday suggests that 75% of Russians believe the US abuses its greater power and only 2% have "a lot of confidence" that Mr Obama will do the right thing in world affairs. Neither of Russia's main TV news bulletins on Sunday evening led with the impending US visit.
"This is being played as essentially a low-key visit that shows the American leadership's respect for the Russian leadership," Dmitry Trenin, head of the Moscow Carnegie Centre think-tank, told Reuters news agency.
"This is not some star coming to town."
Nonetheless, correspondents say Mr Obama can expect a smoother reception than he received on a 2005 visit to Russia when he and other visiting US Congressmen were detained for three hours at an airport in the Urals city of Perm.
They were kept in an "uncomfortably stuffy room adjacent to the tarmac", a US spokesman said, as they resisted Russian customs officials' demands to search their plane.
Mr Obama later brushed off the incident in his book The Audacity of Hope, saying "It wasn't the Gulag".

NKorean launches maybe included new Scud


SEOUL, South Korea (AP) — A barrage of ballistic missiles that North Korea test-fired over the weekend may have included a new type of Scud missile with an extended range and improved accuracy that poses a threat to Japan, a South Korean newspaper reported Monday.

Pyongyang launched seven missiles into waters off its east coast Saturday in a show of force that defied U.N. resolutions and drew international condemnation.

On Monday, South Korea's mass-circulation Chosun Ilbo newspaper reported the launches were believed to have included three Scud-ER missiles with a range of up to 620 miles (1,000 kilometers).

The paper said the Scud-ER has a longer range and better accuracy compared with previous Scud series so is "particularly a threat to Japan."

Tokyo is about 720 miles (1,160 kilometers) from the base on North Korea's east coast from where the missiles were fired. Some other parts of Japan are closer, well within the range of a Scud-ER.

Scuds are single stage, liquid-fueled missiles, originally developed in the former Soviet Union, and generally known for poor accuracy. Ballistic missile programs in Pakistan and Iran were built on Scud technology.

The Chosun Ilbo, citing a government source it did not name, said the other four missiles were two Scud-C missiles with a range of 310 miles (500 kilometers) and two medium-range Rodong missiles that can travel up to 810 miles (1,300 kilometers).

Five of the seven missiles flew about 260 miles (420 kilometers) from an eastern coastal launch site and landed in one area, meaning their accuracy has improved, the paper said.

South Korea's Defense Ministry spokesman Won Tae-jae said Monday that the North demonstrated improved missile accuracy in the latest tests because they all landed in the same area.

He declined to confirm details of the Chosun Ilbo report.

Another ministry official told The Associated Press on Sunday that the missiles appeared to have traveled about 250 miles (400 kilometers), meaning that key government and military facilities in South Korea were within range. The official spoke on condition of anonymity citing department policy.

North Korea has long-range missiles as well. The Taepodong-2 has a potential range of more than 4,100 miles (6,700 kilometers), putting Alaska within striking distance.

The country is believed to be developing a missile with an even longer range that could potentially put the U.S. west coast, Hawaii, Australia and eastern Europe within striking distance.

The launches on July 4 — the U.S. Independence Day holiday — also appeared to be a poke at Washington as it moves to enforce U.N. as well as its own sanctions against the isolated regime for its May 25 nuclear test.

Adm. Mike Mullen, chairman of the U.S. Joint Chiefs of Staff, warned they were "very destabilizing, potentially."

North Korean state media have not specifically mentioned the launches but boasted Sunday that the country's military could impose "merciless punishment" on those who provoke it.

"Our revolutionary forces have grown up today as the strong army that can impose merciless punishment against those who offend us," the North's main Rodong Sinmun newspaper said in a commentary carried by the official Korean Central News Agency.

The North has engaged in a series of acts this year widely seen as provocative. It fired a long-range rocket it said was a satellite in early April, and in late May it carried out its second underground nuclear test following the first in late 2006.

The U.N. Security Council punished Pyongyang with tough sanctions centered on clamping down on North Korea's alleged trading of banned arms and weapons-related material.

The U.S. has been monitoring a North Korean freighter because of suspicions it may be carrying illegal weapons, possibly to Myanmar. The ship, however, turned around a week ago without stopping at any port and headed toward home.

Won, the Defense Ministry spokesman, said the Kang Nam 1 was expected to arrived in the North later Monday.

Separately, in Kuala Lumpur, Malaysian Foreign Minister Anifah Aman pledged to work with the U.S. to block North Korea from using the Southeast Asian nation's banks for any weapons deals.

The assurance came as U.S. envoy Philip Goldberg, in charge of coordinating the implementation of sanctions against Pyongyang, met with Malaysian officials in Kuala Lumpur.

South Korean media have reported that North Korea sought payment through a bank in Malaysia for a suspected shipment of weapons to Myanmar.

Kevin Jonas Gets Engaged!


Kevin Jonas surprised his girlfriend Danielle Deleasa by showing up at her doorstep in New Jersey early Wednesday morning and dropping down to his knee to ask her to marry him. Presented with a cushion-cut diamond ring that Jonas designed with Jacob & Co., Deleasa couldn't believe what was happening. Then, "She said yes, yes, yes like 500 times super fast in a row," the oldest of the Jonas Brothers tells PEOPLE exclusively. Jonas, 21, and Deleasa, 22, who met in May of 2007 while vacationing with their families in the Bahamas, haven't set a wedding date yet. "It still feels like a dream," she tells PEOPLE.
Overnight FlightWhen Deleasa, a former hairdresser, first met Jonas two years ago, she admits, "I didn't know who the Jonas Brothers were." It was Kevin who eagerly pursued her after meeting her and then spotting her walking on the beach with a flower in her hair. Jonas popped the question after arriving in New Jersey on an overnight flight from a concert in Vancouver. "It was tough performing last night, knowing that I was going to ask the biggest question in my life to the most amazing girl in the world," he says. And while the news is bound to break a lot of young girls' hearts, the Jonas family couldn't be happier. "Our hearts are filled with joy today and we are happy to share with you that our son Kevin has asked Danielle for her hand in marriage," parents Denise and Kevin Jonas Sr. say in a statement to PEOPLE. "Her answer was yes, and it is such a blessing that she will be joining our family. Kevin and Danielle have not yet set a date. Family is very dear to us, and we hope we have raised Kevin to be a wonderful man and husband. Please join us in our family's celebration and in congratulating Kevin and Danielle. Thank you for all of your support." And younger brothers Joe and Nick said on their Twitter page: "Congrats big brother.....Dani welcome to the family, we can't wait to have you join us on the road!"

billy mays autopsy report


Billy Mays, who elevated the art of the television sales spiel to a fevered pitch, apparently died of a heart attack, Florida authorities said this morning.Preliminary autopsy results show that Mays suffered from hypertensive heart disease, Hillsborough County Medical Examiner Vernard Adams said during a televised news conference this morning. Toxicology and tissue tests will take several weeks before a final cause of death is issued, he said.
Mays, 50, was found dead in his Tampa home on Sunday after returning to Florida on a commercial flight that sustained a rough landing on Saturday. Mays had said that he had bumped his head during the touchdown.But Adams said the autopsy showed no evidence of trauma to the head, either external or internal.The autopsy showed that Mays' heart was heavier than normal because the left ventricle had enlarged, a symptom of heart disease, Adams said.
Adams said authorities had ruled out prescription drug abuse. Mays was taking prescription painkillers Tramadol and hydrocodone for hip pain, but the pill counts showed that Mays had taken the correct amount, according to the medical examiner

Omni Dual Saw


I was just telling myself the other day I need a more powerful saw. So naturally, like every American in the 21st century, I looked on the Internet. And lo, the gods answered by pointing me to an infomercial
My first thoughts upon beginning the Omni Dual Saw commercial: I wonder if this product is so unique and so powerful that it would take two presenters to tell me about it.
And lo! The gods delivered.The Omni Dual Saw comes with not one, but two announcers: Billy Mays (the man who brought you Oxi-clean, Might Putty, and KaBoom) and Anthony Sullivan (er, the man standing next to Billy Mays)! But if you order now they will throw in Ronco’s Ron Popeil for free!
Now, normally I think it is adorable when couples dress alike, but these two, with their matching khaki’s and denim shirts, put me in mind of Arnold Schwarzenegger and Danny DeVito’s stunt doubles for the movie “Twins”.
And as it turns out the Batman and Robin of TV sales addressed the exact problems I was having in my own personal sawing. Like the hapless handy man in the commercial; I was cutting lumber by wildly flailing my wood saw, trimming tubing by beating it to death with my hack saw, and slicing sheet metal by leering at it aggressively.
Well, as it turns out my problem was none of my saws are inspired by rescue technology. All my tools are inspired by the ingenuity of proud Amish laborers with their century year old unchanged designs. Luddites!
The commercial goes on to show how I can use this dual bladed wonder to cut through a car! This is perfect! You see, I drive a Hummer, but with gas prices as they are; it’s really time I switch to a more effecient mini. I think you see where I’m going with this.
Now cutting through cars is one thing, but is it easy to use? My lord, yes. On screen yelling pioneer Billy Mays explains how it is easy enough for anyone to use and then takes it one step further by showing that anyone can use it! Even a woman! A silly, silly woman! Aren’t they adorable when they try to do manual labor?
Yes, even women can use this saw to cut through their cars quicker than prunes through a short grandma. And it’s the counter rotational technology that makes this saw special. All this time I thought synchronized rotational technology was where the action was. This is truly the greatest thing since sliced bread, and who do you think sliced that bread? Billy Mays!

Obama’s Stance Deflects Chávez’s Finger-Pointing


CARACAS, Venezuela — From the moment the coup in Honduras unfolded over the weekend, President Hugo Chávez had his playbook ready. He said Washington’s hands may have been all over the ouster, claiming that it financed President Manuel Zelaya’s opponents and insinuating that the C.I.A. may have led a campaign to bolster the putschists.

But President Obama firmly condemned the coup, defusing Mr. Chávez’s charges. Instead of engaging in tit-for-tat accusations, Mr. Obama calmly described the coup as “illegal” and called for Mr. Zelaya’s return to office. While Mr. Chávez continued to portray Washington as the coup’s possible orchestrator, others in Latin America failed to see it that way.
“Obama Leads the Reaction to the Coup in Honduras,” read the front-page headline on Tuesday in Estado de São Paulo, one of the most influential newspapers in Brazil, whose ties to Washington are warm.
In recent years, Mr. Chávez has often seemed to outmaneuver Washington on such issues. He exploited the Bush administration’s low standing after the Iraq war and its tacit approval for the brief coup that toppled him in 2002, and blamed the United States for ills in Venezuela and across the region.
Now such tactics may get less traction, as the Obama administration presses for a multilateral solution to the crisis in Honduras by turning to the Organization of American States. In doing so, Mr. Obama is moving away from policies that had isolated the United States in parts of the hemisphere.
“With Honduras, the Obama administration has taken the mainstream road that is more in sync with other countries in the region,” said Peter DeShazo, director of the Americas program at the Center for Strategic and International Studies in Washington.
Honduras, which has long had close ties to Washington, has more recently emerged as a proxy for the interests of both Venezuela and the United States. With subsidized oil, Mr. Chávez lured Honduras into his leftist alliance, the Bolivarian Alternative for the Americas. Meanwhile, the United States did not cut off development and military aid to Honduras, in an attempt to maintain influence there.
But while Mr. Chávez has allies in Bolivia and Ecuador who succeeded in changing constitutions to stay in office longer — following his example in Venezuela — his intervention in Honduras heightened tension in that country. Reports that Venezuela sent a plane to Honduras last week with election material for a referendum at the heart of Mr. Zelaya’s clash with the Supreme Court stirred considerable unease there.
Mr. Chávez portrays his support for Mr. Zelaya as another example of championing his brand of democracy, which often centers on strong presidencies at the expense of other branches of government. But some countries in Latin America are resisting the trend of allowing leaders to extend their stay in office.
In Colombia, for instance, President Álvaro Uribe, a conservative populist and an American ally, is facing difficulties in a push to allow him to run for a third term. And in Argentina, the once popular former president, Néstor Kirchner, admitted defeat this week in congressional elections, throwing into doubt hopes for him and his wife, President Cristina Fernández de Kirchner, to extend their dynasty in the next presidential election.
Meanwhile, Mr. Obama is seeking to engage Brazil more deeply, reportedly floating the appointment of Luiz Inácio Lula da Silva, Brazil’s leftist president, as head of the World Bank. The move, if it materializes, would break the tradition of nominating an American to the post and could bolster support for Washington-based multilateral institutions while blunting Mr. Chávez’s attempts to create his own rival institutions.
Doing this while largely ignoring Mr. Chávez’s taunts holds risks for Mr. Obama, particularly if information comes to light showing that there is some truth in Mr. Chávez’s claims.
The Venezuelan president will not forget that the C.I.A. had knowledge of the coup that ousted him in 2002 yet did nothing to prevent it, and that Washington has a recent history of providing aid to groups that are critical of his government, opening the United States to charges of destabilization.
Moreover, Mr. Chávez’s antiestablishment rhetoric, aimed at elites in Washington and elsewhere, still resounds among many people here in Latin America.
But for now, at least, Mr. Obama’s nonconfrontational diplomacy seems to have caught Mr. Chávez off balance. “Chávez is beginning to understand that he’s dealing with someone with a very different approach than his predecessor,” said Michael Shifter, vice president of the Inter-American Dialogue, a Washington policy research group.
Mr. Chávez’s outsize role in the Honduras crisis, which involved threats of war if Venezuela’s Embassy in Honduras were searched, belies the limits of Venezuela’s influence in the hemisphere as the United States recalibrates its policies in a way that evokes the pragmatic diplomacy of the region’s other power, Brazil.
After the dust settles in Honduras, Mr. Chávez’s alliance will still include some of the region’s poorest and most conflict-ridden nations, like Bolivia and Nicaragua, with larger countries choosing other development paths.
Meanwhile, Mr. Chávez’s threats of belligerence in Central America led one opposition party here, Acción Democrática, to issue a statement on Monday that was full of irony: “Hugo Chávez has become the George Bush of Latin America.”

Franken’s Victory


After nearly eight months of waiting, almost 20,000 pages of legal briefs, and millions of dollars in election costs, Al Franken emerged Tuesday as the next United States senator from Minnesota, ending one of the most protracted election recount battles in recent memory.
Mr. Franken, 58, a former comedian and author, could be seated in the Senate as early as Monday, leaders there said, providing Democrats with something they had long hoped for: 60 votes, and thus at least the symbolic ability to overcome filibusters.
Norm Coleman, a Republican who had held the seat for a term, conceded on Tuesday afternoon, hours after the Minnesota Supreme Court issued a ruling in Mr. Franken’s favor, the latest in a series of findings that had left Mr. Franken ahead in the count. In weeks past, some Republican leaders had urged Mr. Coleman to press on to the federal courts if need be, but those calls faded Tuesday.
“Ours is a government of laws, not men and women,” Mr. Coleman, 59, said in a statement he read before reporters outside his home in St. Paul. “The Supreme Court of Minnesota has spoken, and I respect its decision and will abide by the result. It’s time for Minnesota to come together under the leaders it has chosen and move forward. I join all Minnesotans in congratulating our newest United States senator — Al Franken.”
It was an oddly abrupt ending to an election contest that had left Senator Amy Klobuchar, a Democrat, handling the state’s business alone and had left many ordinary Minnesotans weary of the fight.
All along, the candidates had been separated by the slightest of margins. With 2.9 million Minnesotans casting ballots last November, one early count showed Mr. Coleman ahead by 206 votes. Then, in a statewide hand recount set into motion by the close vote, the numbers fluctuated in the estimations of the campaigns and others trying to track them. Ultimately, a three-judge panel announced that Mr. Franken had won by 312 votes.
In issuing its 5-to-0 opinion, the Supreme Court found that Mr. Coleman, who had argued, in part, that thousands of absentee ballots had been wrongly excluded from the count, had failed to prove that “the trial court’s findings of fact are clearly erroneous or that the court committed an error of law or abused its discretion.”
Late Tuesday afternoon, outside his town house in downtown Minneapolis, Mr. Franken appeared jubilant at a news conference that at times looked more like an election-night rally. Passersby stopped, and one called out: “We have a senator! We have a senator!”
“When you win an election this close, you know that not one bit of effort went to waste,” said Mr. Franken, who has already hired senior staff to prepare for his transition to the Senate. His wife, Franni, had for months kept a packed suitcase at the ready like an expectant mother, Ms. Klobuchar said, should the family be called to Washington for a swearing-in.
President Obama called Mr. Franken to congratulate him on Tuesday, aides said, and he issued a statement saying he looked forward to working with the senator-elect “to build a new foundation for growth and prosperity by lowering health care costs and investing in the kind of clean energy jobs and industries that will help America lead in the 21st century.”
Gov. Tim Pawlenty, a Republican, signed Mr. Franken’s election certificate early Tuesday evening. Senate Democrats said they would like to seat Mr. Franken as quickly as next week, giving the party a crucial vote as it moves to difficult debates over topics like climate change and health care.
Democrats had held some committee posts for Mr. Franken, potentially including the Health, Education, Labor and Pensions Committee that is in the middle of drafting a health care overhaul.
With 60 votes (including those of two independents) now most likely aligned with the Democrats, the party could avoid filibusters.
But Mr. Franken swiftly made it clear that he did not view himself as the Democrats’ No. 60. “That’s not how I see it,” he said, adding that he was “going to be the second senator from the state of Minnesota, and that’s how I’m going to do this job.”
Though Republicans expressed disappointment at the outcome, they had in recent weeks become increasingly resigned to Mr. Franken joining the Senate.
On Tuesday, they joined Mr. Coleman in acknowledging defeat and immediately sought to raise expectations for Democrats.
“With their supermajority, the era of excuses and finger-pointing is now over,” said Senator John Cornyn of Texas, who heads the National Republican Senatorial Committee. Mr. Cornyn said it was “troubling to think about what they might now accomplish with 60 votes.”
But whether Democrats can consistently rely on 60 senators being present is in question. Two veteran Democrats, Senators Robert C. Byrd of West Virginia and Edward M. Kennedy of Massachusetts, are ailing and have regularly been absent from the Senate. In addition, a handful of moderate to conservative Democrats have shown a willingness to break from the party, and even liberals will do so on some issues.
In the Twin Cities, there was widespread relief on Tuesday. Minnesotans are viewed as among the nation’s most politically engaged and involved voters, but even there, patience had grown thin. “It went on forever,” Paul Mathey, 70, of St. Paul, complained.
The race was not the only long standoff in Senate history, nor was it the longest. Among others, the 1974 race between John A. Durkin and Louis C. Wyman left the Senate seat from New Hampshire in doubt for 10 months. The election was finally resolved when the seat was declared vacant and a special election was held, declaring Mr. Durkin, a Democrat, the winner in September 1975.
This time, the battle ended with a phone call between two men who had appeared to talk only through their opposing lawyers and spokesmen for months.
On Tuesday afternoon, Mr. Coleman called Mr. Franken to tell him he was giving up. Mr. Coleman, who some in Minnesota were already speculating might run for governor in 2010 (for now, he would not comment) described the call as “a very personal discussion, a very positive discussion.”
Mr. Franken said that the two had talked about the difficulty of the long fight on their families, and that Mr. Coleman had told him, “This is going to be the best job you’ll ever have.”
After so much turmoil, the phone call was warm and gracious, Mr. Franken said, adding later that he had recalled thinking in the midst of it: “This is nice. This is a nice way to end it.”

Another celebrity falls prey to death rumors singer Rick Astley


Another hour, another celebrity death rumour. This time the story is that 80’s pop sensation Rick Astley was found dead in a German hotel room. Here’s the very official-looking news report that’s making the rounds - I haven’t been able to verify it, so don’t start putting together your Rick Astley tribute on your MySpace page just yet.

Singer-Songwriter Rick Astley Found Dead in Berlin Hotel Room

By LIZ SIDOTI

The Associated Press

Monday, June 30, 2009 1:00 AM

Berlin — Known for his 80’s pop hit “Never Gonna Give You Up,” the 43-year-old Rick Astley has been pronounced dead today. Astley’s body was found at the Angleterre Hotel in Berlin after an ambulance responded to an emergency call from his hotel room.

Astley was found unconscious in his hotel bedroom and was unable to be resuscitated. He was pronounced dead on the scene.

Astley was in the middle of a concert tour that would have ended in late August of 2009. He was to return to the United Kingdom at that time.

© 2009 The Associated Press

So, is this yet another celebrity passing or have we all been Rick Rolled? I have a feeling it’s the latter, and I’m sure Astley’s wife, producer Lene Bausager would find any of these rumors amusing and I imagine it would be especially hard on his daughter, Emilie. To all of you out there who are starting these death rumours - remember there’s a kid somewhere who would be devastated to hear that a parent has died.

Don Cornelius Reminisces Michael


Don Cornelius, the creator and host of the long-running TV musical institution 'Soul Train,' reminisces about when he discovered the prodigious and precocious musical talents of the late Michael Jackson."I met Michael Jackson at the age of 8, when his father and my new friend, Joe Jackson, first began to bring the Jackson 5 to Chicago, from their home in Gary, Indiana, for concert appearances," Cornelius tells Spinner. "The word of the Jackson 5's devastating abilities as concert artists had already begun to spread like an out-of-control forest fire to the laser-like attention of all Chicago area R&B music stars."The prevailing thought process among local R&B stars with respect to this very young group of entertainers known as the Jackson 5 had become, 'If Michael Jackson and his brothers were booked on an upcoming Chicagoland show, leave it alone! Don't book it! Don't go on that show and get completely blown away by young Michael and the Jackson 5!'"In regard to the superstar that 8-year-old boy would become, Cornelius has this to say: "Michael Jackson's personal crescendo of amazing power as an entertainer was clear and unmistakable, and has never slowed to this very day! His passing will be grieved far beyond that of any other singer, composer, producer, dancer and choreographer in the history of the world. Indeed, in my very firmest personal belief, there will never, ever, be another Michael Jackson!"

Gene Predicts How Brain Responds To Fatigue, Human Study Shows


New imaging research in the June 24 issue of The Journal of Neuroscience helps explain why sleep deprivation affects some people more than others. After staying awake all night, those who are genetically vulnerable to sleep loss showed reduced brain activity, while those who are genetically resilient showed expanded brain activity, the study found. The findings help explain individual differences in the ability to compensate for lack of sleep.

"The extent to which individuals are affected by sleep deprivation varies, with some crashing out and others holding up well after a night without sleep," said Michael Chee, MBBS, at the Duke–National University of Singapore Graduate Medical School, an expert on sleep deprivation who was not affiliated with the study. However, studying how the brain produces these behavioral differences is difficult: researchers usually do not know whether their study participants will be vulnerable to sleep deprivation until after a study is complete. Previous studies have shown conflicting results, perhaps because the study subjects differed widely in vulnerability to sleep deprivation.

In the current study, the researchers, led by Pierre Maquet, MD, at the University of Lìege in Belgium and Derk-Jan Dijk, PhD, at the University of Surrey in the United Kingdom, avoided this problem by selecting study participants based on their genes. Previous research showed that the PERIOD3 (PER3) gene predicts how people will respond to sleep deprivation. People carry either long or short variants of the gene. Those with the short PER3 variant are resilient to sleep loss — they perform well on cognitive tasks after sleep deprivation. However, those with the long PER3 variant are vulnerable — they show deficits in cognitive performance after sleep deprivation. Now the new study explains why.

The authors imaged study participants while they did a working memory task that requires attention and cognitive control — also called executive function. The researchers imaged each participant four times: the night before and the morning after a good night's sleep, and the night before and morning after a sleepless night.

They found that the resilient, short gene variant group compensated for sleep loss by "recruiting" extra brain structures. In addition to brain structures normally activated by the cognitive task, these participants showed increased activity in other frontal, temporal, and subcortical brain structures after a sleepless night.

In contrast, after a sleepless night, vulnerable participants, the long PER3 group, showed reduced activity in brain structures normally activated by the task. These participants also showed reduced brain activity in one brain structure — the right posterior inferior frontal gyrus — after a normal waking day. These data are consistent with previous research suggesting that people with the long gene variant perform better on executive tasks earlier, but not later, in the day.

"Our study uncovers some of the networks underlying individual differences in sleep loss vulnerability and shows for the first time how genetic differences in brain activity associate with cognitive performance and fatigue," said study author Maquet. "The data also provide a basis for the development of measures to counteract individual cognitive deficits associated with sleep loss," he said.

"This study and others like it could help in identifying those who may be at risk for performance decline in jobs where sleep deprivation is an integral feature, for example- all-night health care staff, senior decision makers, commercial aircraft pilots, and truck drivers. Such knowledge might also guide the development of more effective, possibly personalized countermeasures for at-risk people," said Chee, the expert unaffiliated with the study.

The Belgian Fonds de la Recherche Scientifique, Queen Elizabeth Medical Foundation, University of Lìege, Interuniversity Attraction Pole – Phase V, Wellcome Trust, and Biotechnology and Biological Sciences Research Council supported the research.

Rating Attractiveness: Consensus Among Men, Not Women, Study Finds


Hot or not? Men agree on the answer. Women don't.

There is much more consensus among men about whom they find attractive than there is among women, according to a new study by Wake Forest University psychologist Dustin Wood.

The study, co-authored by Claudia Brumbaugh of Queens College, appears in the June issue of theJournal of Personality and Social Psychology.

"Men agree a lot more about who they find attractive and unattractive than women agree about who they find attractive and unattractive," says Wood, assistant professor of psychology. "This study shows we can quantify the extent to which men agree about which women are attractive and vice versa."

More than 4,000 participants in the study rated photographs of men and women (ages 18-25) for attractiveness on a 10-point scale ranging from "not at all" to "very." In exchange for their participation, raters were told what characteristics they found attractive compared with the average person. The raters ranged in age from 18 to more than 70.

Before the participants judged the photographs for attractiveness, the members of the research team rated the images for how seductive, confident, thin, sensitive, stylish, curvaceous (women), muscular (men), traditional, masculine/feminine, classy, well-groomed, or upbeat the people looked.

Breaking out these factors helped the researchers figure out what common characteristics appealed most to women and men.

Men's judgments of women's attractiveness were based primarily around physical features and they rated highly those who looked thin and seductive. Most of the men in the study also rated photographs of women who looked confident as more attractive.

As a group, the women rating men showed some preference for thin, muscular subjects, but disagreed on how attractive many men in the study were. Some women gave high attractiveness ratings to the men other women said were not attractive at all.

"As far as we know, this is the first study to investigate whether there are differences in the level of consensus male and female raters have in their attractiveness judgments," Wood says. "These differences have implications for the different experiences and strategies that could be expected for men and women in the dating marketplace."

For example, women may encounter less competition from other women for the men they find attractive, he says. Men may need to invest more time and energy in attracting and then guarding their mates from other potential suitors, given that the mates they judge attractive are likely to be found attractive by many other men.

Wood says the study results have implications for eating disorders and how expectations regarding attractiveness affect behavior.

"The study helps explain why women experience stronger norms than men to obtain or maintain certain physical characteristics," he says. "Women who are trying to impress men are likely to be found much more attractive if they meet certain physical standards, and much less if they don't. Although men are rated as more attractive by women when they meet these physical appearance standards too, their overall judged attractiveness isn't as tightly linked to their physical features."

The age of the participants also played a role in attractiveness ratings. Older participants were more likely to find people attractive if they were smiling.

Pastor defends exorcism of gay man


A pastor defended a video posted on YouTube of an exorcism of a gay man, saying her church does not hate gay people, it just does not believe in their lifestyle.

The video, which has sparked outrage among gay-rights advocates, shows a young man writhing around on the floor at the Manifested Glory Ministries church in Stamford, Conn., as elders cast a "homosexual demon" from his body.

The video, which was taken six or seven months ago, has since been removed from the Web site. It is not clear who posted it.Pastor Patricia McKinney said the man in the video told the nondenominational church "he did not want to live this way."

"Every Sunday we call people up to the altar who want to be delivered from any spirit that causes them to not be able to function," McKinney told CNN on Thursday. "We were just beginning to worship the Lord and all of a sudden he hit the floor."

She described the man, whom she did not identify, as very religious and spiritual.

"Manifested Glory Ministries is not against homosexuality. We do not hate them. We do not come up against them. We do just not believe in their lifestyle," McKinney explained.

'Casting shame'
One religious figure said he understood the man's situation because he went through the same experience.

The Manifested Glory Ministries was "acting out of ignorance by equating homosexuality to demon possession," the Rev. Roland Stringfellow, of the Center for Lesbian and Gay Studies in Religion and Ministry of Berkeley, Calif., told Reuters.

Stringfellow said he was exorcised twice at a different church when he asked for help to deal with his own homosexuality.

"This young man who obviously went for help ended up being damaged I believe," he said. "I am concerned about the emotional and spiritual scars he has. I felt what they were doing was casting not a demon out, but casting shame."The uproar over the video coincides with gay-pride week, marking the 40th anniversary of the Stonewall riots in New York City's Greenwich Village that triggered the modern U.S. gay-rights movement. The annual march through Manhattan is set for Sunday.

A push for gay marriage to be legalized has gathered momentum around the United States and is already allowed Massachusetts, Connecticut and Iowa. Gay couples will be allowed to marry in Vermont starting in September and New Hampshire in January.

Some states provide for same-sex unions that grant many of the same rights as marriage. Forty-two U.S. states explicitly prohibit gay marriage, including 29 with constitutional amendments, according to Human Rights Campaign, a gay-rights advocacy group.

Booby-trapped motorcycle kills 11 in Baghdad


BAGHDAD - A booby-trapped motorcycle exploded in a crowded bazaar Friday in Baghdad, killing at least 11 people and wounding dozens, Iraqi officials said.
It was the latest in a week of attacks that have killed some 200 people ahead of next week's deadline for U.S. troops to withdraw from urban areas in Iraq.
The explosion occurred just after 9 a.m. when the market was packed with young people buying or selling motorcycles under the shadow of a Sunni mosque in central Baghdad, police and hospital officials.Nobody claimed responsibility for the attack, but insurgents frequently target crowded market districts to try to maximize casualties. The motorcycle bazaar is only open on Fridays.
The market has been hit by several bombings in the past, but Iraqis have resumed flocking to the area due to security gains that have sharply driven down the level of violence.
Police and hospital officials, who spoke to The Associated Press on condition of anonymity because they weren't authorized to release the information, gave the death toll and said more than 40 people also were wounded.

‘Great victory’?

The escalation in violence is undermining Prime Minister Nouri al-Maliki's declaration of a "great victory" in the U.S. pullout from urban areas by Tuesday's deadline. He has declared June 30 a national holiday to be marked with celebrations.
U.S. and Iraqi officials have warned they expect more violence in the days surrounding the deadline but insist the withdrawal will go ahead as scheduled.
Under a security pact, the Americans must pull back from cities by June 30 and from the entire country by the end of 2011. But the continued violence has raised concerns about the readiness of Iraqi security forces to protect the people.

Farrah Fawcett dies from cancer at 62


Actress Farrah Fawcett, whose layered blonde mane and ubiquitous swimsuit poster transformed the once-unknown "Charlie's Angels" star into a '70s icon, died Thursday. She was 62.
Fawcett - who waged a three-year battle against anal cancer - died shortly before 9:30 a.m. in a Santa Monica, Calif., hospital, said her spokesman, Paul Bloch.
The Texas-born actress chronicled her valiant fight for survival in a two-hour documentary. Her longtime love, actor Ryan O'Neal, was at her bedside with Fawcett's 91-year-old father, friend Alana Stewart, hairdresser Mela Murphy and doctor Lawrence Piro when the sex symbol passed away.
"After a long and brave battle with cancer, our beloved Farrah has passed away," O'Neal said in a statement.
"Although this is an extremely difficult time for her family and friends, we take comfort in the beautiful times that we shared with Farrah over the years and the knowledge that her life brought joy to so many people around the world."
Stewart, in a statement, said she was devastated by the death of her close friend of 30 years.
"Although I will miss her terribly, I know in my heart that she will always be there as that angel on the shoulder of everyone who loved her," Stewart said.
Fawcett's co-stars from "Charlie's Angels" also mourned the loss of their friend.
"Farrah had courage, she had strength, and she had faith," said Jaclyn Smith. "And now she has peace as she rests with the real angels."
Cherly Ladd recalled Fawcett as "incredibly brave ... God will be welcoming her with open arms."
Just days before her death, O'Neal said he hoped Fawcett would hang on long enough for them to wed.
"I've asked her to marry me, again, and she's agreed," O'Neal, 68, told Barbara Walters in a "20/20" interview.
"As soon as she can say yes," he said. "Maybe we can just nod her head."
The former pinup traveled the world in search for a cure for her disease, allowing cameras to capture her treatment and inner thoughts.
"I know that everyone will die eventually, but I do not want to die of this disease. I want to stay alive," she said.
"So I say to God, because it is, after all, in his hands: It is seriously time for a miracle."
By the time the documentary "Farrah's Story" aired in mid-May to 9 million viewers, Fawcett was gravely ill, too sick to attend her own premiere. And the miracle she prayed for never came.
Fawcett burst into the national consciousness during the Bicentennial, debuting in September 1976 as one of three gorgeous female investigators on "Charlie's Angels."

"King of pop" Michael Jackson dies at 50


Michael Jackson, 50, died yesterday in Los Angeles as sensationally as he lived, as famous as a human being can get. He was a child Motown phenomenon who grew into a moonwalking megastar, the self-anointed King of Pop who sold 750 million records over his career and enjoyed worldwide adoration. But with that came the world's relentless curiosity, and Mr. Jackson was eventually regarded as one of show business's legendary oddities, hopping from one public relations crisis to another.
In the end there were two sides to the record: The tabloid caricature and the provocative, genre-changing musical genius that his fans will always treasure. There were those whose devotion knew no bounds, who visited the gates of his private ranch north of Santa Barbara, Calif., arriving at Neverland on pilgrimages from Europe and Asia, and who were among the first to flock to UCLA Medical Center as news of his death spread yesterday afternoon. Those were the same kind of fans who camped out at the Santa Barbara Superior Courthouse, to show their support during his 2005 trial. They released doves and wept when he was acquitted.
Then there was the other kind of fan, who preferred to keep memories of the singer locked firmly in his 1980s prime: Today's young adults all have memories of being toddlers and grade-schoolers who moonwalked across their mother's just mopped kitchen floors. Even the hardest rockers will easily confess to the first album they ever bought: "Thriller."
"I am just dev-as-tated," said Bridgette Cooper, 44, of Mitchellville, who was driving her children to math tutoring when her 12-year-old got the news by text. "I don't ever remember not loving him. I have been a fan forever. Even through the turmoil and the public spectacle, I still loved him and his music."
Mr. Jackson's death set off an instant media frenzy befitting the later chapters of his celebrityhood. The singer suffered an apparent heart attack at one of his residences in Bel-Air. Paramedics said Jackson was not breathing when they arrived at 12:26 p.m. Pacific time. The singer was brought to the UCLA Medical Center at 1:14 p.m. PDT and pronounced dead at 2:26 (5:26 Eastern).
Web sites began reporting that the singer had been taken to the hospital. Soon, streets in the Westwood neighborhoods around the hospital were clogged with traffic as crowds of onlookers formed, much as they did wherever the singer had appeared. Soon enough, they were dancing and playing Mr. Jackson's music, as a helicopter flew away with his body, en route to the coroner. All around the world, from Los Angeles to Adams Morgan to Times Square to Tokyo and beyond, people cued up Mr. Jackson's songs -- some digging out cassettes and LPs.
Mr. Jackson's brother, Jermaine, told reporters that "it is believed [Mr. Jackson] suffered cardiac arrest" and that the star's personal physician had tried to revive him. Jermaine Jackson then asked for something his family is unlikely to get in the next several days: privacy. "And may Allah be with you, Michael, always," he said.
"For Michael to be taken away from us so suddenly at such a young age, I just don't have the words," producer Quincy Jones said. "To this day, the music we created together on 'Off the Wall,' 'Thriller' and 'Bad' is played in every corner of the world and the reason for that is because he had it all . . . talent, grace, professionalism and dedication. He was the consummate entertainer and his contributions and legacy will be felt upon the world forever. I've lost my little brother today, and part of my soul has gone with him."
"On the one hand, it's shocking," said Alan Light, a journalist who has edited Spin and Vibe magazines. "On the other, everybody had the sense that there was not going to be a happy ending to this story. I don't know what other final chapter there was going to be. . . . It's almost impossible to overstate the impact he had on popular music and popular culture. He really defined what the music video could be. He was the ultimate crossover figure, bringing black music and rock-and-roll together. He is someone who will be remembered as an absolute superstar. He may have lost some of his popularity in the United States, but he remained a superstar in corners of the world not visited by other artists."
Mr. Jackson's career began as a family business in Gary, Ind. As the Jackson 5, the group moved in a comparatively short time from local talent contests to national stardom, with the encouragement of established artists including Gladys Knight. Driven by their father in a borrowed Volkswagen van, the Jackson 5 appeared in Chicago, at New York's Apollo Theater and as the opening act for the Temptations and Smokey Robinson and the Miracles. At Knight's urging, Motown owner Berry Gordy signed the group to a contract in 1968.
Two years later, when Michael was 12, the Jackson 5 had four No. 1 hits, including "ABC" (which won a Grammy Award as best pop song) "I Want You Back" and "I'll Be There." Under Gordy's intensive grooming, the Jackson 5 achieved an astounding degree of mass popularity among black and white audiences. Their concerts caused near-riots, with young Michael becoming an unlikely prepubescent sex symbol and a Saturday morning cartoon.
Mr. Jackson began to emerge as a solo artist with the album "Got to Be There" (1971), which included the hit song "Rockin' Robin."
At 15, his voice broke, giving him a range from soprano to tenor. At the same time, the Jacksons began to chafe under the strict artistic control of Gordy and demanded greater artistic freedom. In 1975, the Jacksons left Motown for CBS's Epic label, but Gordy managed to keep the rights to the Jackson 5 name. Michael and his brothers continued performing as the Jacksons, and in 1978 Michael sang and danced as the Scarecrow in the film "The Wiz," an all-black remake "The Wizard of Oz" starring one of Jackson's idols, Diana Ross.
Jones, who produced "The Wiz's" soundtrack, agreed to produce Mr. Jackson's next solo album. Their first collaboration, "Off the Wall" (1979), sold 9 million copies and had four Top 10 hits. In 1982, Mr. Jackson released his next, "Thriller," which was also produced by Jones. It became an instant phenomenon, selling more than 40 million copies globally and yielding seven Top 10 hits, including "Billie Jean," "Beat It" and the title track.
"Thriller" won eight Grammy Awards, but it was Mr. Jackson's breathtaking performances on music videos accompanying the album that became instantly memorable. He choreographed the exciting dance routines, which featured his showstopping moonwalk, acrobatic moves and uncanny precision. He started wearing a white glove on one hand, which became one of his sartorial signatures. Several guest stars, including Paul McCartney, Eddie Van Halen and Vincent Price, appeared on videos from the album.
His 1987 album, "Bad," sold 30 million copies and produced five No. 1 singles, including the title track, "I Just Can't Stop Loving You" and "Man in the Mirror." Videos from the album dominated MTV. By the time of his 1991 album, "Dangerous," Mr. Jackson had parted ways with producer Jones. Although the album sold 32 million copies, it was seen as something of an artistic letdown.
In his 30s, Mr. Jackson started to become more enigma than entertainer. He straightened his hair and nose, beginning a process of almost surreal self-reconstruction. In time, Jackson's skin turned from brown to a pale, ghostly white, his nose shrank from repeated plastic surgery, and his frame remained painfully gaunt. He wore outlandish costumes in public, spoke in an airy, high-pitched whisper.
His world devolved into a series of tabloid headlines that reported rumors or facts about everything from his curious pet ownership to the plastic surgeries that drastically changed him. He built a private playland, the sprawling Neverland, replete with an amusement park and zoo, to which he invited scores of underprivileged children. He was accused of abusing a child in the 1990s (a case which was settled out of court in 1994 for a reported amount between $15 million and $24 million).
For all his impact on popular music, Mr. Jackson's life seemed to play out as a metaphor on the delusions and cruelty of fame. He was unlucky in the art of public relations, and sometimes he was just unlucky, as when pyrotechnics set his hair on fire during the filming of a Pepsi commercial.
Other misfortunes he seemed to bring on himself -- and theories about his behavior were never in short supply. People loved to think they had cracked the mystery of Michael: He wanted his face to resemble Liz Taylor's. He hated his appearance because his father and brothers used to tease him. He was repressed, he was asexual, he was an addict, he was a pervert, he was from outer space, he was a genius, he was stupid, he was insane. The truth was never known and Jackson recoiled from media scrutiny, and largely thwarted the assistance of image experts, who displeased him.
In the early 2000s his fortunes and recording contracts waned, and an album, 2001's "Invincible," essentially tanked, selling only 10 million copies worldwide. Mr. Jackson lashed out at his record label and claimed, at an appearance with the Rev. Al Sharpton, that he was the victim of racism. The hits kept not coming, but the headlines did: In November 2002, Jackson appeared to dangle his blanketed infant son over a Berlin hotel balcony while greeting fans and paparazzi below, which brought outrage.
He was briefly married to Elvis Presley progeny Lisa Marie Presley -- a largely symbolic union of pop dynasties. After that marriage was over, he became a father to three children, whose paternal and maternal origins created much speculation: Prince Michael I, who is now 12, and Paris Michael, 11. His youngest child, Prince Michael II (nicknamed Blanket as a baby), is 7. (He is also survived by his siblings and his parents, Joe and Katherine Jackson.)
"I must confess I am not surprised by today's tragic news," Michael Levine, a Los Angeles publicist who represented Mr. Jackson when the singer was accused of child molestation in the 1990s, said in a statement. "Michael has been on an impossibly difficult and often self-destructive journey for years. His talent was unquestionable but so too was his discomfort with the norms of the world. A human simply can not withstand this level of prolonged stress."
Mr. Jackson was planning to appear in a sold-out series of concerts in London next month that would have run until March. Promoters of the concerts had recently said that the singer had passed a physical examination to assuage any doubts he was ready for a comeback.
But what sort of comeback? It seemed increasingly futile. Michael Jackson's many observers (a media cottage industry all its own) generally regard a 2003 television interview he gave as the beginning of his end. In that interview, with British journalist Martin Bashir, Mr. Jackson appeared holding hands with a young boy who had cancer. Something seemed weird. Something always seemed weird.
That particular weirdness eventually led Mr. Jackson back to court in the spring of 2005, after the boy accused the pop star of molesting him. Mr. Jackson's fragility was never more pronounced than in that Santa Maria courthouse. Here at last was the daily, up-close look at a withered man in a mirror, under the courtroom's fluorescent lights. He was always polite, and always sad. Mr. Jackson was acquitted and spent the rest of his days on the move, on jets and in hotels, dodging bankruptcy proceedings, as if he were on the run from not only what he was, but what the world made him.

Why the Recession Is Good

Since the financial crisis began, Suze Orman—the queen of personal finance—has been criticized for everything from her conservative investment choices to not having predicted the recession. The author of nine personal finance books, including The Money Book for the Young, Fabulous, and Broke, has changed some of her advice, most notably that consumers should pay only the minimum amount required on their credit cards until they set up an eight-month emergency fund. But in general, her parentlike admonitions for consumers to take charge of their money and not be "stupid" have only become more urgent. U.S. News spoke with Orman about the crisis and what people should do with their money now. Excerpts:
USN.load('Loomia');

What surprised you most about the current financial crisis?
That it happened at all.
So you didn't see it coming?
I saw real estate coming down; I saw the stock market might be a little whatever. Did I ever, in my wildest dreams, think it would possibly bring down the entire economy of the world? No. Why didn't I think that? I will tell you. I believed the CEOs that went on television and looked in the cameras and told everyone it was going to be OK, that they were fine.
Why did I believe them? I believed them because do you think a normal human being, which I am, would think that after Enron, after WorldCom, after all those debacles and Sarbanes-Oxley and having to sign financial statements, would any CEO be that stupid to go on national television where everything is recorded and look in the camera and lie through their teeth? In a million years, I never thought that would happen.
Do you think you and other financial experts could have done a better job of anticipating the crisis?
I'm a personal finance expert. My expertise is not as an economist, not as a stock market guru, not as a precious metal predictor, or in interest-rate foreshadowing. My job is to look at what happened in the economy and what is going on in the world of finance and to tell people, based on fact, this is what's happening now; this is what you need to do with your personal money. To that end, I think I was really far and above anybody else, and I got attacked for it.
Do you ever worry that by telling Americans to spend less, you will help slow the economy further?
No, because what good does it do to spend money they don't have, to put it on the credit cards? All of a sudden, they lose their job, get sick, or get hit by a car. I can give youstories that are unbelievable. Here you're in a situation where you put going out to eat, [paying for] gym memberships, and getting manicures on a credit card. Now you can't pay anything on your credit cards. Banks can't survive. They're taking TARP [Troubled Asset Relief Program] money. So it's like, if you feel OK with taxpayers paying for the fact that you have DVDs and televisions, then go ahead, keep spending.
Our problems aren't that we aren't spending money. Our problems were that we were spending money that we never had. We were spending money we couldn't afford to spend. That was the solution to the economy—to continue to get yourself in debt.
A lot of people have lost their company 401(k) matches. Should they still put money in?
If your 401(k) does not match and you have credit card debt, hands down, pay off the credit card. However, if you have credit card debt and do not have an eight-month emergency fund or have no emergency fund whatsoever, then do you pay just the minimum or pay off the debt? You pay the minimum on cards, and you save for your emergency fund. I don't care what anybody tells me, what anybody says. Anyone who said they should do something other than that is someone who lives behind a computer screen and is not out talking to people. . . . [Credit card companies] are indiscriminately—across the board—revoking credit cards and reducing credit limits.
Do you think young people have it worse than any other generation, with their higher unemployment rate, high debt levels, and weak job market for graduates?
Right now, they have it so great it's not even funny.